Aiyuk's agent Drew Rosenhaus told ESPN's Adam Schefter on Wednesday that Aiyuk has filed paperwork for reinstatement from the reserve/left-squad list and will report to the 49ers' facility Friday. Aiyuk hasn't played since Oct. 20, 2024, when he tore his ACL, MCL and meniscus. 49ers GM John Lynch and coach Kyle Shanahan have repeatedly said Aiyuk has played his last snap in San Francisco — Shanahan's one-word answer when asked about a reunion was "no" — so the likelier outcome if he's reinstated is a release rather than a return to the 49ers' WR room.
Fantasy take
Aiyuk's medical clearance has been the gating issue since late 2025, not just a front-office standoff; filing for reinstatement signals he's ready to be activated off the left-squad list, which is the step that precedes either a return to practice or a trade/release. With Evans, Samuel, Pearsall, Kirk, Watkins, Cowing and Robinson all ahead of him on the depth chart, reinstatement looks like the mechanism for a transaction rather than a path back onto the field there. Where he ends up, and whether he's fantasy-relevant this season, still depends on a trade or release that hasn't happened yet.