injuryLamar Jackson's ankle under evaluation after MRI
Jackson left Baltimore's 24-18 win over Tennessee in the second half after Titans DE Jermaine Johnson II sacked him on the final snap of the first half, rolling his left ankle. He exited the stadium in a walking boot and had an MRI Monday. NFL Network's Ian Rapoport said the Ravens are hopeful Jackson plays Week 5 against the Falcons and consider him day-to-day; Tyler Huntley ran the offense the rest of the way.
Fantasy take
Baltimore has been through this before: Jackson missed four games with a hamstring in 2025, and his rushing numbers never fully recovered when he returned, averaging barely half his career carries-per-game the rest of the way. An ankle is a different joint, but it's the same leg that provides most of his fantasy margin over a standard passer. Huntley has run this offense in relief before and moved the ball competently without much power behind his arm — 426 yards and 2 touchdowns on 67 attempts a year ago, with Baltimore's rushing identity leaning harder on Henry whenever he's in at QB.
injuryJayden Daniels targets Oct. 11 return; Mariota re-hurt
Commanders coach Dan Quinn said Monday that Daniels (elbow) is aiming for a full week of practice with the goal of starting Sunday, Oct. 11 against the Giants — the first firm target the team has set since his dislocation. Backup Marcus Mariota re-aggravated his right MCL and left Sunday's loss to the Colts in the first quarter; rookie Athan Kaliakmanis finished that game at QB3, going 15-for-33 for 186 yards and a touchdown.
Fantasy take
Monday's plan for a full practice week is the first firm target the team has set since the dislocation. Through seven games this season he carried 58 times for 278 yards and 2 touchdowns, so a clean Oct. 11 return puts the run game back in the offense alongside Croskey-Merritt and White rather than leaving it to Mariota or Kaliakmanis under center. The elbow is the same one he dislocated last November, and it's already cost him two different stretches of games in two years — Washington's optimism this week doesn't change that it's shown up twice now.
injuryEagles enter London game thin at RB and WR1
Tank Bigsby will have core-muscle surgery and go on injured reserve, out at least four weeks, after aggravating the injury late in Sunday's 24-20 loss to the Rams; Ian Rapoport reported hopes he's back "in six weeks or shorter." Saquon Barkley (hamstring) is week-to-week, with Nick Sirianni saying he'll have more answers Wednesday — that leaves Will Shipley as the lead back for Sunday's game against the Jaguars in London. DeVonta Smith (hamstring) is "at very best questionable" for the same game.
Fantasy take
Shipley has 14 carries and 12 targets on the season heading into this workload shift, a bit-part role rather than a proven one. Barkley's hamstring and Bigsby's surgery both landing in the same week leave Philadelphia without its top two backs for London, and Sirianni's Wednesday timeline on Barkley is the next real data point rather than this week's. Smith sitting at "very best questionable" on a hamstring of his own means the receiving operation could be without its leading receiver in the same game the backfield turns over. Three banged-up pieces in one unit for one road trip is a different situation than any one of these ailments in isolation.
injuryBengals: Chase in concussion protocol, Higgins day-to-day
Bengals coach Zac Taylor said Monday that Ja'Marr Chase is in the NFL's concussion protocol after taking a hit early in the second quarter of Sunday's loss to the Jaguars, with no clearance timeline given. Taylor described Tee Higgins as day-to-day with an adductor injury from the same game and said the team will build a rehab plan starting Wednesday, calling a potential return against Miami "great" if he can go.
Fantasy take
Chase's concussion protocol and Higgins' adductor injury put Cincinnati's top two target earners out of the same loss, in a passing game that has leaned on Chase for a career-high 30.4% target share this season. Higgins has posted 148, 114, and 60 receiving yards in the three prior games Chase has missed, the only data available on how the room redistributes targets without him — but Miami week risks both receivers sitting simultaneously, a scenario with no recent precedent.
transactionsSeahawks sign Joe Mixon
The Seahawks are signing free-agent RB Joe Mixon after a Monday workout, per ESPN's Adam Schefter. The move comes as Seattle's backfield thins — rookie Jadarian Price is on injured reserve with a chest injury, and Zach Charbonnet is still working back from his Achilles tear on a recently activated 21-day practice window. Mixon, 30, missed all of 2025 and last played for Houston in 2024, when he ran for 1,016 yards and 11 touchdowns.
Fantasy take
Wilson has carried the Seahawks' early-season rushing load this year with 125 carries for 496 yards and 3 scores on roughly 30% of offensive snaps, while Holani has stayed clearly behind him with 22 carries and 20% of snaps. Mixon's addition drops into that structure as the new name above both of them, arriving off a year away from football and a 2024 line of 245 carries for 1,016 yards and 11 touchdowns in Houston. Darnold's backfield now holds Mixon alongside Wilson, Holani, and Velus Jones Jr. while Charbonnet works back from his Achilles and Price sits on injured reserve. The questions the workout and signing don't answer are how quickly Mixon is active and how the carries split once he is.